Association between polygenic effect and environmental factors in Alzheimer's disease Lead Investigator: Masataka Kikuchi Institution : Osaka University E-Mail : kikuchi@gi.med.osaka-u.ac.jp Proposal ID : 1373 Proposal Description: 1) Our goal is to examine whether a combination of polygenic effect and environmental factors is more precisely explain AD pathology. 2) We will compare predictive accuracy by only the polygenic effect and that by a combination of polygenic effect and environmental factors. We will use Nagerkelke's pseudo R2 statistic.